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Study on the clinical synergistic anti-fungal effect of choline-geranate ionic liquid and ketoconazole

Randomized controlled clinical trial of ketoconazole-loaded ionic liquids in local treatment of fungal infection

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035486
Enrollment
Unknown
Registered
2020-08-12
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tinea corporis and tinea pedis

Interventions

Experimental group:The test group was treated with KCZ-IL emulsion, and the subjects applied an appropriate amount of the drug to the affected area once or twice a day for 4-6 weeks.
Control group:The control group received the treatment of commercial preparation jintaoning cream
Subjects will apply appropriate amount of medicine to the affected area once or twice a day for 4-6 weeks.

Sponsors

Shanghai Skin Disease Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. the patients and their families all signed the informed consent form, which was approved by the ethics committee of our hospital; 2. they all met the clinical diagnostic criteria of tinea pedis and tinea corporis and cruris, and were diagnosed by various examinations; 3. those with good mental or consciousness were able to follow the arrangement of medical staff for treatment.

Exclusion criteria

Exclusion criteria: 1. pair of patients with drug allergy in the study; 2. those who had taken antibiotics before the study; 3. pregnant or lactating women, and those with a history of antifungal treatment within 1 month.

Design outcomes

Primary

MeasureTime frame
Symptoms of tinea corporis & cruris;Fungus inspection;

Secondary

MeasureTime frame
Pathological examination of skin;Detecting the index of oxidative stress reaction quantitatively;

Countries

China

Contacts

Public ContactXiying Wu

Shanghai Skin Disease Hospital

wxyifd@163.com+86 15001794105

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026