Pancreatic cancer
Conditions
Interventions
Lidocaine Group :Intravenous infusion of lidocaine
Control Group:Intravenous infusion of saline
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. aged 18 to 70 years old; 2. resectable pancreatic head cancer diagnosed; 3. ECOG stage 0-2; 4. More than 2 weeks from the end of the last chemotherapy; 5. Total bilirubin level =10 g/dL, platelet count greater than 100x10^9/L; 7. serum creatinine <2.5 ULN; 8. have carefully read and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Diagnosed as unresectable pancreatic cancer; 2. ASA grade greater than grade 3; 3. Patients with a history of local anesthetic drug allergy; 4. History of severe sinus block and other arrhythmia; 5. Currently receiving any of the following class I antiarrhythmics Drug treatment: Quinidine, Flecainide, Disopyramide or Procainamide; 6. Previous use of amiodarone hydrochloride treatment; 7, Autoimmune disease patients or untreated and untreated type B or C Hepatitis; 8. Have a history of pulmonary embolism or deep vein thrombosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease-free survival;Postoperative complication rate;Length of Stay; | — |
Countries
China
Contacts
Public ContactChen Wankun
Zhongshan Hospital, Fudan University
Outcome results
None listed