Atrial fibrillation
Conditions
Interventions
Experimental group:Cryotherapy combined with radiofrequency ablation for maze IV procedure
control group:Radiofrequency ablation for maze IV procedure
Sponsors
Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with mitral valve disease requiring surgical treatment and a history of paroxysmal / persistent atrial fibrillation (evidence includes any of the following: atrial fibrillation was recorded by Holter or 12 lead ECG); 2. Patients who are willing to participate in the study, follow-up trials and evaluation procedures with informed consent; 3. Patients aged 18-80 years.
Exclusion criteria
Exclusion criteria: 1. Patients who have had previous atrial fibrillation ablation or cardiac surgery; 2. Patients with other organic heart diseases: Patients with other severe valvular disease, congenital heart disease, coronary heart disease and dilated cardiomyopathy except for mitral valve disease, who need other cardiac surgery except atrial fibrillation ablation at the same time; 3. Patients with other serious arrhythmias; 4. Patients with EF 65mm; 6. Malignant tumor, active infection, pregnant or lactating objects; 7. Patients with life expectancy less than 1 year; 8. Patients with hyperthyroidism; 9. Patients with other hemorrhagic diseases who can not be treated with anticoagulant therapy; 10. Patients with poor general condition and multiple organ dysfunction who are expected to be unable to tolerate surgery; 11. Patients who are not expected to complete the follow-up; 12. Patients who are unwilling or unable to comply with the study protocol; 13. Patients considered by other researchers to be unsuitable for this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rhythm; | — |
Secondary
| Measure | Time frame |
|---|---|
| Atrial flutter;Atrial tachycardia;Heart rate;Left heart function;Rate of withdrawal from antiarrhythmic drugs;Stroke;Systemic embolism;Heart failure;Rehospitalization rate; | — |
Countries
China
Contacts
Public ContactJu Mei
Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University
Outcome results
None listed