Pulmonary infectious disease
Conditions
Interventions
Gold Standard:Biopsy histological examination
,mNGS
Sponsors
Shanghai Pulmonary hospital affiliated to Tongji University
Eligibility
Sex/Gender
All
Age
1 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. This study is limited to lung biopsy and surgical specimens, including transbronchial biopsy, CT or ultrasound-guided biopsy and surgical biopsy (lung wedge biopsy / lobectomy, thoracotomy or thoracoscopic assistance); 2. The presence of granulomatous inflammation is confirmed by 2 pathologists; 3. The clinical information of the included patients is recorded as baseline information, including age, gender, immune status, body temperature, whole blood cell count, ESR, C-reactive protein, sputum smear, microbial immunology and serological tests, and whether empirical antibiotic therapy was performed.
Exclusion criteria
Exclusion criteria: 1. Patients who are unable to carry out all the tests required for the study due to unqualified tissue samples; 2. Patients who have stopped or lost follow-up due to various reasons; 3. Patients with severe cardiopulmonary diseases and HIV positive patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mNGS; | — |
Countries
China
Contacts
Public ContactWenwen Sun
Shanghai Pulmonary Hospital Affiliated to Tongji University
Outcome results
None listed