Cervical cancer
Conditions
Interventions
Experimental group:bone marrow sparing intensity modulated radiotherapy
Sponsors
Shanghai Jiao Tong University Affliated Sixth People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Cervical cancer patients diagnosed by pathology for the first time; 2. According to the 2014 FIGO cervical cancer staging for patients with stage IB-IVa; 3. Aged from 18 to 70 years old; 4. ECOG general condition score 0-2, weight loss less than 10% within 6 months, can tolerate radiotherapy and chemotherapy; 5. No other second primary cancer within 5 years; 6. It is confirmed that there is no distant metastasis by MRI or CT, chest X-ray, B-ultrasound, etc.; 7. No other serious medical complications such as coronary heart disease, hypertension, tuberculosis, etc.; 8. Non-pregnancy and lactation period; 9. Those who are expected to survive more than 12 months; 10. Laboratory examination before radiotherapy and chemotherapy meets the following conditions: blood function: absolute neutrophil count (ANC) >=2x10^9/L, platelet count >=100x10^9/L and hemoglobin >=9g/dL; 11. The subject agrees and signs the informed consent form (if the subject is not capable of judgment, his legal guardian is required to sign the informed consent form).
Exclusion criteria
Exclusion criteria: 1) Accompanied by other malignant tumors, including malignant tumors discovered at the same time and in the past; 2) Combined with hematological diseases; 3) Past medical history of pelvic radiotherapy; 4) Patients with severe liver, kidney and nervous system diseases and mental illness; 5) Circumstances where other examiners believe that there are sufficient reasons to be unqualified from the registration study: if there is a potential inconsistency with the clinical plan, etc.; 6) Unable or unwilling to sign informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Local recurrence; | — |
Countries
China
Contacts
Public ContactXiaojing Yang
Department of Radiation Oncology, Shanghai Jiao Tong University Affliated Sixth People's Hospital
Outcome results
None listed