hepatocellular carcinoma
Conditions
Interventions
Gold Standard:Pathological diagnosis
Index test:miRNA7
Sponsors
Zhongshan Hospital Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-90 years old, male or female; 2. no malignant tumor lesions were found by ultrasound (US) or MRI/CT, or showed no lesions with the typical characteristics of HCC: "fast in and fast out" (obvious enhancement of lesions in arterial phase and decreased enhancement of portal vein or delayed phase); 3. miRNA7 test result is positive; 4. People at high risk of liver cancer (have at least one risk factor below): (1) Hepatitis B virus infection: HBV surface antigen positive and/or HBV DNA positive; (2) HCV infection: HCV RNA positive; (3) the patient was clinically diagnosed as non-alcoholic fatty liver hepatitis; (4) Patients clinically diagnosed with cirrhosis or liver biopsy diagnosed with cirrhosis; (5) people with a family history of liver cancer in first-degree or second-degree relatives.
Exclusion criteria
Exclusion criteria: 1. People who do not meet the inclusion criteria or meet the inclusion criteria but unwilling to participate 2. People with unclear background information; 3. People with malignant disease or have a history of tumor; 4. People with systemic immune diseases or serious cardiovascular and cerebrovascular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver ultrasound; | — |
Countries
China
Contacts
Public ContactJie Hu
Zhongshan Hospital Fudan University
Outcome results
None listed