Postoperative Pain
Conditions
Interventions
Group S:sufentanil 2.0µg/kg + granisetron 2mg + normal saline to 120ml
Group SN1:sufentanil 2.0µg/kg +nalbuphine 0.2 mg/kg + granisetron 2mg + normal saline to 120ml
Group SN2:sufentanil 2.0µg/kg +nalbuphine 0.4 mg/kg + granisetron 2mg + normal saline to 120ml
Group SN3:sufentanil 2.0µg/kg +nalbuphine 0.8 mg/kg + granisetron 2mg + normal saline to 120ml
Sponsors
Department of Anaesthesiology and Perioperative Medicine, The Second Hospital of Anhui Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients undergoing laparoscopic hysterectomy; 2. ASA I-II; 3. Aged 40- 65 years; 4. BMI (Body Mass Index) 18.5~25 kg/m2; 5. With normal communication and certain learning ability; 6. Having signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Serious respiratory or circulatory diseases: such as severe atherosclerosis of coronary artery, cardiac failure, myocardial infarction, respiratory failure; 2. Neurological diseases: such as severe cerebral hemorrhage or cerebral infarction , hemiplegia or aphasia; 3. Mental illness: such as schizophrenia or depression; 4. Long-term abuse of drugs: including chemotherapy drugs and analgesics; 5. Obvious liver or kidney dysfunction; 6. Pregnant and lactating women; 7. Allergy to opioid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;total PCIA and supplementary analgesia;post-operative quality of sleep; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay score;patients’ satisfaction; | — |
Countries
China
Contacts
Public ContactXianwen Hu
The Second Hospital of Anhui Medical University
Outcome results
None listed