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Lenalidomide in maintenance treatment of primary central nervous system lymphoma

Lenalidomide in maintenance therapy of primary central nervous system lymphoma: a prospective cohort study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035401
Enrollment
Unknown
Registered
2020-08-10
Start date
2020-08-01
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary CNS Lymphoma

Interventions

Trial group:Lenalidomide

Sponsors

Huashan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) The age is 65-80 years old, both male and female; 2) Non Hodgkin's lymphoma was diagnosed by histopathology and immunohistochemical staining, and no systemic LYMPHOPOIETIC tissue or other system involvement was found after strict physical examination and auxiliary examination; 3) PET-CT showed complete remission after chemotherapy; 4) The subjects read and fully understood the patient's instructions and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Combined with other malignant tumors; 2) Severe heart failure, liver dysfunction or renal insufficiency; 3) Severe arrhythmia; 4) Pregnancy or lactation of women; 5) Recent participants in other clinical trials; 6) Other major diseases or mental disorders.

Design outcomes

Primary

MeasureTime frame
PFS;relapse rate;

Secondary

MeasureTime frame
ORR;OS;Incidence of adverse reactions;

Countries

China

Contacts

Public ContactYan Ma

Huashan Hospital, Fudan University

mayan1024@126.com+86 13621762629

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026