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A comparative study of ctDNA detection in peritoneal lavage fluid in the diagnosis of colorectal cancer peritoneal metastasis

A comparative study of ctDNA detection in peritoneal lavage fluid in the diagnosis of colorectal cancer peritoneal metastasis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035400
Enrollment
Unknown
Registered
2020-08-10
Start date
2020-10-28
Completion date
Unknown
Last updated
2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

peritoneal metastasis of colorectal cancer

Interventions

Gold Standard:Pathological diagnosis
Index test:Sensitivity&#32
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detection&#32
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Sponsors

The Sixth Affiliated Hospital, Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Aged 18-85 years; 2) the experimental group: patients with preoperative pathological diagnosis of colorectal cancer, imaging examination or intraoperative pathological diagnosis of peritoneal metastasis. 3) Control group:Preoperative pathological diagnosis of colorectal cancer, imaging examination to exclude patients with peritoneal metastasis. 4) The patients can fully understand the informed consent form and sign the informed consent form voluntarily. 5) The functions of important organs (including heart, liver, kidney) are sufficient and can tolerate the risk of operation and anesthesia.

Exclusion criteria

Exclusion criteria: 1) Patients with tumor bleeding; 2) Patients with moderate to large ascites; 3) Unable to obtain surgical or puncture tissue samples; 4) Previous history of malignant tumors.

Design outcomes

Primary

MeasureTime frame
sensitivity;specificity;

Secondary

MeasureTime frame
Positive predictive value;Negative predictive value;Diagnostic power;

Countries

China

Contacts

Public ContactZixu Yuan

The Sixth Affiliated Hospital, Sun Yat-Sen University

yuanzx5@mail.sysu.edu.cn+86 18820107381

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026