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The survival value of primary tumor resection in metastatic colorectal cancer based on tumor biological behavior

The survival value of primary tumor resection in metastatic colorectal cancer based on tumor biological behavior

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035397
Enrollment
Unknown
Registered
2020-08-10
Start date
2020-08-01
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Sponsors

The First Affiliated Hospital of Tsinghua University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Pathological diagnosis of colorectal cancer adenocarcinoma; 2. Unresectable metastases besides asymptomatic or mild primary tumors; 3. No prior treatment for metastases; 4. All patients with complete clinical and ollow-up data; 5. Aged 20~75 years; 6. Existing measurable objective tumor lesions which could be evaluated with RECIST 1.1 criteria; 7. ECOG (Eastern Cooperative Oncology Group) 0-1 and expected survival period for 6 months or more; 8. Good-enough functions of heart, liver, kidneylungs and bone marrow; 9. Informed consent must be signed by patients and/or their legal guardians..

Exclusion criteria

Exclusion criteria: 1. Diagnosis with brain metastasis or bone metastasis; 2. Diagnosis with a history of tumor other than colorectal cance; 3. Requirement of operation intervention for perforation, bleeding and obstruction of intestinal cavity; 4. Follow-up data and medical history are incomplete; 5. Diagnosis with severe underlying diseses, such as severe organ dysfunction and infection, etc.; 6. Poor compliant patients.

Design outcomes

Primary

MeasureTime frame
Progression Free Survival;

Secondary

MeasureTime frame
Overall survival;Complications related with primary tumor during chemotherapy;Postoperative complications;Living quality;Tolerance to treatment;

Countries

China

Contacts

Public ContactLi Zhao

The First Affiliated Hospital of Tsinghua University

zhaoli7505@hotmail.com+86 15911028958

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026