Skip to content

The influence of different corneal transplantation methods (DMEK, DSEK, PK) on the efficacy and complications of corneal endothelial diseases

The influence of different corneal transplantation methods (DMEK, DSEK, PK) on the efficacy and complications of corneal endothelial diseases

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035396
Enrollment
Unknown
Registered
2020-08-10
Start date
2014-08-30
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal endothelial disease

Interventions

1:DMEK
2:DMEK
3:DMEK
4:DSEK
5:DSEK
6:DSEK
7:PK
8:PK
9:PK

Sponsors

Zhongshan Ophthamic Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Clinically diagnosed with ICE syndrome (advanced) or Fuchs endothelial dystrophy or corneal endothelial decompensation, which meets all diagnostic criteria; 2) aged 18 to 70 years old; 3) voluntary cornea Transplant treatment and sign the surgical consent form with the doctor. Adults are signed by the patients themselves, and minors are signed by their legal representatives. Adults with poor eyesight who cannot sign can be signed by the client, and the patients themselves will be confirmed by fingerprints; 4) Females of childbearing age are not during regular holidays.

Exclusion criteria

Exclusion criteria: 1) those with other ocular diseases; 2) those with systemic diseases, especially autoimmune diseases; 3) those with a history of internal eye surgery; 4) those who are pregnant; 5) Those who cannot cooperate or tolerate the operation.

Design outcomes

Primary

MeasureTime frame
Corrected distance visual acuity (CDVA);endothelial cell loss (ECL);

Secondary

MeasureTime frame
IOP;graft survival;

Countries

China

Contacts

Public ContactTing Huang

Zhongshan Ophthamic Center

thuang@vip.163.com+86 13682205425

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026