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Prospective cohort study and predictive model construction of the relationship between the characteristics of reproductive tract flora of early pregnancy women and early pregnancy outcomes

Prospective cohort study and predictive model construction of the relationship between the characteristics of reproductive tract flora of early pregnancy women and early pregnancy outcomes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035378
Enrollment
Unknown
Registered
2020-08-09
Start date
2020-07-15
Completion date
Unknown
Last updated
2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spontaneous abortion, tubal pregnancy

Interventions

Sponsors

The First Affiliated Hospital of Guangzhou Traditional Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Female aged >=18 years; 2. The menopause time 4-8 weeks; 3. The blood HCG is positive and the pregnancy location is not clear; 4. Participate voluntarily in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who took antibiotics or antifungal drugs within 30 days before sample collection 2. Patients who have had sex with vaginal or cervix topical medication or irrigation within 48 hours before sample collection; 3. Patients with acute inflammation of the genital tract at the time of specimen collection, or a history of tumor; 4. Patients who have a lot of vaginal bleeding during specimen collection, which may affect the quality of the specimen.

Design outcomes

Secondary

MeasureTime frame
ph (vaginal secretion);leucocyte esterase (vaginal secretion);Vaginal discharge hydrogen peroxide;Vaginal discharge hydrogen peroxide;Vaginal secretions sialidase;Vaginal secretions beta-glucuronidase;Vaginal secretions Acetylglucosaminidase;serum hCG;serum progesterone;serum estradiol;

Primary

MeasureTime frame
ultrasound;

Countries

China

Contacts

Public ContactJie Gao

The First Affiliated Hospital of Guangzhou Traditional Chinese Medical University

gjfkts@qq.com+86 13760605046

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026