Alveolar site preservation
Conditions
Interventions
A:Single tooth missing+CPC-I type
B:Single tooth missing + CPC-II type
C:Two teeth missing + CPC-I type
D:Two teeth missing + CPC-II type
Sponsors
The Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male or female patients older than 18 and less than 65 years old; 2. Single root teeth in bilateral anterior teeth or premolar area, single tooth or continuous double teeth need site preservation before implant restoration; 3. The subjects with mesial and distally adjacent teeth in position and not missing; 4. Subjects without diabetes and other systemic diseases; 5. The width of buccal lingual bone was not enough in the implant position; 6. The subjects with enough horny gums in the alveolar ridge (from the midline of the crest to the gingival membrane joint >=2mm); 7. The subjects voluntarily signed the informed consent form before carrying out any research related trial steps.
Exclusion criteria
Exclusion criteria: 1. Patients with local inflammation of adjacent teeth, including uncontrolled periodontitis (periodontal probing depth > 4mm); 2. Patients with untreated acute and chronic apical periodontitis in their adjacent teeth; 3. Patients with oral mucosal lesions (such as lichen planus); 4. Patients with space occupying lesions (including cysts, tumors, etc.) in the adjacent teeth; 5. Patients with systemic diseases affecting bone healing, wound healing and dental implant therapy (if stable diabetes is not controlled, fasting blood glucose is still >=8.8 mmol / L after drug control); 6. Patients with severe hypertension without stable control; 7. Contraindications of conventional implant surgery and oral surgery, including bone graft surgery; 8. Patients with heart disease (grade II and above heart function disease); 9. Patients with liver and kidney dysfunction or abnormal; 10. In obese patients, BMI > 28 kg / m2; 11. Patients who have received full dose radiotherapy, local radiotherapy of head or neck; 12. Patients who need long-term high-dose steroid therapy; 13. Patients who are receiving or have received drugs (such as bisphosphonates) that may affect or promote bone metabolism in recent 3 months; 14. Patients who received antibiotic therapy or chronic anti-inflammatory therapy (more than 3 times a week) in the first 4 weeks before surgery; 15. Patients with alcoholism or long-term drug abuse; 16. Patients with immune insufficiency; 17. Patients who smoked / tobacco equivalent / chewed more than 10 cigarettes a day; 18. Patients with physical or mental defects that affect oral health care; 19. Patients allergic to products; 20. Pregnant or lactating female patients; 21. Patients with poor compliance who could not participate in the trial according to the researchers; 22. Within 30 days prior to the start of surgery (study day 0), patients participated in clinical trials of other drug devices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alveolar bone width change; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alveolar bone height;Alveolar bone volume;Gum thickness;Gingival papilla height; | — |
Countries
China
Contacts
Public ContactYiqun Wu
The Ninth People's Hospital Affiliated to medical school of Shanghai Jiaotong University
Outcome results
None listed