Stroke
Conditions
Interventions
Control group:Routine rehabilitation training
Sponsors
The First Affiliated Hospital of Shenzhen University, Shenzhen Second People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of stroke; 2. Patients with stable vital signs; 3. Patients aged >=18 years old; 4. Onset time 15 Days-1 year; 5. Patients with Mrs grade 4 or 5; 6. Patients with at least one lower limb who can actively complete hip and knee extension; 7. Patients with a score of coordination degree s5q >=3, who can understand and actively participate in the evaluation and training program; 8. Patients or family members sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Subjects with unstable vital signs, including respiratory rate >=35 beats / min or increase >=50%; SpO2 40%); heart rate >=145 beats / min or continuous increase >=20% compared with that before the test; systolic blood pressure >=180mmhg or =38.5 degree or =200 u/L, or AST >=200u/L; 5. Patients with other serious diseases, such as malignant tumor, end stage of chronic kidney disease, mental disorder, severe malnutrition, etc; 6. Patients with nonunion of lower limb fracture and severe osteoporosis; patients with high muscle tension and Ashworth grade 2-4; 7. Patients with untreated DVT; 8. Pregnant or lactating women; 9. Patients who participated in clinical trials of other drugs or medical devices during the same period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| left ventricular ejection fraction, LVEF;NT-proBNP;stroke volume, SV;cardiac output, CO; | — |
Secondary
| Measure | Time frame |
|---|---|
| vital capacity, FVC;FEV1;FEV1/FVC; | — |
Countries
China
Contacts
Public ContactMingling Huang
Shenzhen Second People's Hospital (the First Affiliated Hospital of Shenzhen University)
Outcome results
None listed