polycystic ovarian syndrome
Conditions
Interventions
PCOS group:Nil
control group:Nil
Sponsors
Union Hospital affiliated to Huazhong University of Science and Technology
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. PCOS group: Meet the diagnostic criteria of Rotterdam in 2003: (1) Patients with rare ovulation or even no ovulation; (2) The clinical symptoms or biochemical manifestations of the patient showed hyperandrogenemia; (3) Color ultrasound of the abdomen showed polycystic ovary changes (vaginal color ultrasound showed that one or both ovaries contained more than 12 follicles of 2-9mm); If two of the three criteria are met, a diagnosis can be made. 2. Control group: (1) Normal menstrual cycle (28-35 days); (2) No clinical symptoms of excessive androgens; (3) Normal serum androgen level; (4) No polycystic changes were observed in abdominal color doppler ultrasound; (5) There is no history without education. 3. Age: 18~50 years old women of childbearing age. 4. Did not receive any oral contraceptives, other forms of hormonal contraception or fertility treatment for at least 3 months, and did not receive progesterone treatment for at least 1 month prior to study participation. 5. Never received any cholesterol-lowering drug, antihypertensive drug, insulin sensitizer, metformin or any other diabetes 6. Did not take any sedatives or antidepressants for at least 3 months.
Exclusion criteria
Exclusion criteria: (1) Pregnant and lactating women. (2) Patients with thyroid diseases and hyperprolactinemia. (3) Patients who have undergone ovarian or uterine surgery. (4) Patients with congenital adrenal hyperplasia, Cushing's syndrome, androgen secreting tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hospital Anxiety and Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sex hormone levels;blood lipid level;fasting blood-glucose;fasting insulin; | — |
Countries
China
Contacts
Public ContactLiu Yi
Outcome results
None listed