knee osteoarthritis, KOA
Conditions
Interventions
Sponsors
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: The diagnostic criteria of KOA refer to the guidelines for the diagnosis and treatment of osteoarthritis (2018 edition) formulated by the Chinese society of traditional Chinese medicine in 2018. (1) repeated pain in past one month; (2) X-ray film (standing position or weight-bearing position) showed knee joint space narrowing, subchondral osteosclerosis and/or cystic change, osteophyte formation at joint edge; (3) aged >=50 years; (4) The morning stiffness time <=30min; (5) With bone friction sound (feeling). Meet (1) + any 2 of (2), (3), (4), (5) iteams can be diagnosed as knee osteoarthritis.
Exclusion criteria
Exclusion criteria: (1) For inflammatory arthritis (such as rheumatoid or psoriatic), this study will test subjects for rheumatoid factors, blood sedimentation and anti-o before inclusion, excluding the possibility of rheumatoid arthritis; (2) The coagulation dysfunction; (3) Previous hip/knee replacement surgery or planning to undergo hip/knee surgery during the trial; (4) Patients with knee joint tumor, tuberculosis, suppuration and disease affecting joint structure and function; (5) At the same time, the local use of external treatment, such as local treatment; (6) Patients with diseases that hinder participation in and influence the completion of the study, such as myocardial infarction or stroke, congestive failure, severe chronic obstructive pulmonary disease, cancer, diabetes, severe systemic disease, and severe mental illness in the past three months; (7) Local skin scar is not suitable for intervention, such as: psoriasis, toxic neuropathy, etc.; (8) Any test drugs being used in the past 30 days; (9) At the same time to participate in other clinical trials, unable to complete the instruments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale;WOMAC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Model of the Knee;Biomechanical characteristics;Security indicators; | — |
Countries
China
Contacts
Public ContactDu Jiong
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed