dry eye
Conditions
Interventions
experimental group:Wear scleral contact lens
Sponsors
The Huadong Hospital affliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Patients between the ages of 18 and 60; 2) Tear film breakup time (TBUT) < 5 s; 3) Schirmer I test <= 5 mm/5min; without surface anesthesia; 4) Corneal fluorescein staining score greater than 2 points; 5) Subjects are fully familiar with the study and voluntarily participate in this clinical trial and sign informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with acute inflammatory infection in ocular horn conjunctiva; 2) Dry-eye patients who had received subtear embolization, tarsal gland thermal pulse and optimized intense pulse light in half a year; 3) Autoimmune disease patients; 4) There are other eye diseases need long-term eye drops patients, such as glaucoma, anterior uveitis and other diseases; 5) Patients with obvious allergic constitution; 6) Is taking oral hormone or receiving eye hormone treatment patients; 7) Pregnant or lactating women who plan to conceive in the near future; 8) Patients in other clinical trials within the last 3 months; 9) Patients with progressive severe disease (cancer); 10) Failure to follow up on schedule or to cooperate with researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TBUT; | — |
Secondary
| Measure | Time frame |
|---|---|
| OSDI Questionnaire;SChirmer test;Lachrymal height;corneal fluorescein staining;Conjunctival lisamine green;osmotic pressure of tears;Corneal topography;Refraction;lipid; | — |
Countries
China
Contacts
Public ContactWu Rong
The Huadong Hospital affliated to Fudan University
Outcome results
None listed