chronic apical periodontitis
Conditions
Interventions
Gold Standard:Histopathological analysis
Index test:Magnetic resonance imaging
Sponsors
The Ninth People's Hostpital affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >18 years; 2. There is still a periapical radiolucency after perfect root canal treatment; 3. Root canal retreatment is not feasible, such as the existence of large restorations, broken instrument in the canal or overfills that cannot be removed, perforations that cannot be repaired by non-surgical treatment, etc.; 4. Root canal retreatment failed; 5. Severe root canal anatomy variation; 6. Need to confirm the diagnosis through exploratory surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with surgical contraindications; 2. Metal alloy restorations or appliances in the oral; 3. Claustrophobia 4. Those who are allergic to gadopentetate meglumine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| enhanced area;ratio of enhanced area-to-lesion area;sensitivity;specificity;receiver operating characteristic of curve;area under receiver operating characteristic of curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| signal intensity of lesion edge on T2WI;signal intensity of lesion center on T2WI;ratio of max thickness on contrast-enhanced T1WI(T1WI+C) to average of length and width of lesion;ratio of max thickness to average of length and width of lesion;maximum thickness of lesion on T2WI;Apparent diffusion coefficient (ADC) of leision edge;average of ADC;enhanced amplitude of signal intensity;maximum thickness of lesion on T1WI+C;false positive rate;false negative rate;positive predictive value; negative predictive value;accuracy;Youden's index;likelihood Ratio; | — |
Countries
China
Contacts
Public ContactHuang Zhengwei
The Ninth People's Hostpital affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed