Gastroesophageal reflux disease with hiatal hernia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Between January 2012 and July 2020, GERD patients with HH (aged =18 years old) who underwent laparoscopic HH repair combined with different antireflux operations in the Department of Intervention of First Affiliated Hospital of Zhengzhou University were recruited. GERD with HH was diagnosed according to the Guidelines for the diagnosis and management of gastroesophageal reflux disease"[1-2] and HH diagnosis criteria[8-9]. Indications for the operation were as follows: ineffective medical treatment (uncontrollable severe reflux or intolerable side effects of antacids), serious esophagitis, esophageal stenosis, Barrett's esophagus, and external symptoms (such as reflux-related asthma, reflux-related cough, reflux-related pneumonia, and reflux-related sleep disorder) seriously affecting the quality of life and requiring surgery.
Exclusion criteria
Exclusion criteria: Patients with gastroptosis, superior mesenteric artery compression syndrome, achalasia, achalasia Heller myotomy, other operations of the esophagus or stomach, severe cardiovascular and cerebrovascular diseases, respiratory system diseases, liver and kidney dysfunction, blood system diseases, malignant tumors, and/or other intolerable conditions. In addition, pregnant women and patients with mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The operative time; intraoperative blood loss; postoperative hospital stay; postoperative 1.5-year or three-year efficacy; and within 3-year readmission and postoperative complications; | — |
Countries
China
Contacts
The First Affiliated Hospital of Zhengzhou University