Local Administration of Tranexamic Acid on Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery

Effect of Intramedullary Irrigation with Tranexamic Acid on Blood Loss in Patients Undergoing Intertrochanteric Fracture Surgery: a Random Controlled Trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035215

Enrollment

Unknown

Registered

2020-08-04

Start date

2020-09-01

Completion date

Unknown

Last updated

2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intertrochanteric femoral fracture

Interventions

Intramendullary irrigation with low concentration of TXA:Intramedullary irrigation with 0.5g/100mlTXA in 5 minutes

Intramendullary irrigation with standard concentration of TXA:Intramedullary irrigation with 3g/100mlTXA in 5 minutes

Intravenous administration of TXA:Intravenous administration with 0.5g/100mlTXA 30minutes before surgery

Blank Control:Intravenous administration with normal saline 30minutes before surgery

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients over 60 years old; 2. The patients with intertrochanteric fracture were diagnosed; 3. The surgical treatment was proximal femoral nail fixation.

Exclusion criteria

Exclusion criteria: 1. Patients with coagulation dysfunction: hemophilia, etc.; 2. Patients with long-term oral anticoagulants; 3. Patients who have received blood transfusion before operation.

Design outcomes

Primary

Measure	Time frame
RBC;Hb;Hct;	—

Countries

China

Contacts

Public ContactQifang He

Hangzhou First People's Hospital

heqifang1982@126.com+86 13575728939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026