Recurrent aphthous ulcer
Conditions
Interventions
Control group:Placebo
Sponsors
Peking University School and Hospital of Stomatology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for recurrent aphthous ulcer; (2) The clinical classification is mild recurrent oral ulcer; (3) The course of the disease should not exceed 48 hours, and no treatment has been performed; (4) Aged 18-65 years, male or female.
Exclusion criteria
Exclusion criteria: (1) Patients with other obvious painful lesions that may affect the observation of curative effect, such as: patients with pericoronitis, acute pulpitis, acute apical inflammation and other diseases; (2) Having used analgesics, antibiotics, anti-inflammatory drugs 48 hours before the study, and having used corticosteroids, immunomodulators and other western medicines with the same or similar effects within three months; (3) Those who are accompanied by other diseases, such as the circulatory system, endocrine system, digestive system, malignant tumors, and autoimmune diseases; (4) Patients with severe cardiovascular, cerebrovascular, severe cardiopulmonary insufficiency, liver, kidney, hematopoietic system and other serious primary diseases, diseases, mental disorders, and intellectual disabilities; (5) People with allergies and a history of allergies to drugs and food; (6) Pregnant and intentional pregnancy women or lactating women; (7) Those who have participated in clinical trials within the past three months; (8) The investigator believes that it is not suitable to participate in clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ulcer size;Ulcer healing rate;Pain score;Ulcer healing time;Safety evaluation; | — |
Countries
China
Contacts
Public ContactHong Hua
Peking University School and Hospital of Stomatology
Outcome results
None listed