Pancreatic cancer
Conditions
Interventions
Group 1:adequate fluid supplementation
Group 2:GDFT
Sponsors
Department of Anesthesiology, Ruijin Hosptial affiliated to Shanghai Jiao Tong University School of Medician
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing pancreatic tumor surgery in this research center; 2. Aged >=18 years; 3. ASA level 1-2; 4. The patient had no serious complications of heart, lung and kidney diseases, and no serious metabolic diseases; 5. The patient was not preoperatively accompanied by intestinal obstruction, intestinal perforation, severe liver and kidney function injury and other diseases; PTCD, ENBD and other gastrointestinal operations were not performed; 6. Did not receive probiotic treatment within one year before surgery; No history of antibiotic use within 3 months before surgery.
Exclusion criteria
Exclusion criteria: 1. No stool samples were collected within 2 days before surgery and 6-8 days after surgery; 2. Unexpected secondary surgery patients before postoperative stool samples were collected; 3. Take laxative for intestinal preparation within 2 days before surgery; 4. Preoperative cardiac ultrasound examination of the patient showed LVEF < 50% and myocardial infarction occurred in the past three months; Lung function test FEV1 < 50%; Renal insufficiency, blood creatinine level exceeded the upper limit of normal value by 50%; 5. Preoperative infection, severe endocrine disease, severe blood system disease, nervous system disease, cerebrovascular disease history and mental disease; 6. Patients with severe allergies and short-term massive blood loss during the operation need to be rescued. 7. Patients who have concerns about this study and are unwilling to accept it.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diversity of intestinal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative infusion volume; | — |
Countries
China
Contacts
Public ContactLu Xiaojian
Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed