Acute respiratory failure
Conditions
Interventions
experimental group:bag-valve mask ventilation with 10cmH2O positive end-expiratory pressure
control group:bag-valve mask ventilation
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. The patient is older than 18 years old; 2. Patients requiring endotracheal intubation in the ED for acute respiratory failure will be recruited. Acute respiratory failure is defined as a respiratory rate higher than 30/min, dyspnea at rest, a partial arterial oxygen pressure (PaO2) less than 60 mmHg on room air, or a PaO2 divided by the fraction of inspired oxygen (FiO2) less than 300 regardless of supplemental oxygen provided; 3. The patient and his/her family agree to have endotracheal intubation and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Maternity; 2. Acute circulatory failure before intubation: hypotension requiring vasoactive drug therapy to maintain mean blood pressure over 65 mmHg; 3. Cardiac arrest before intubation; 4. Expected airway difficulty: the MACOCHA score was used to evaluate the airway as difficult; 5. The presence of right-to-left shunt heart disease and long-term hypoxia; 6. Difficulty in mask ventilation: insufficient mask sealing, excessive air leakage or excessive ventilation resistance; 7. Patients requiring urgent endotracheal intubation and difficulty in completing adequate preoxygenation time were assessed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;Use of vasoactive medicine;Incidence of aspiration; | — |
Countries
China
Contacts
Public ContactXujun
Peking Union Medical College Hospital
Outcome results
None listed