knee osteoarthritis
Conditions
Interventions
Ozone group:30µg/ml articular cavity injection of 15ml ozone
Genicular nerve block group:Genicular nerve block 2 times
Combined use group:Ozone combined with genicular nerve block
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for knee osteoarthritis in the Guidelines for the Diagnosis and Treatment of Osteoarthritis (2018 edition); (2) Between the ages of 50 and 85 years; (3) Duration of unilateral or bilateral knee pain >= 1 month; (4) In the recent 3 months, he did not receive any invasive treatment for the knee (such as lumen injection and acupuncture treatment); (5) Volunteer to participate in this experimental study and sign the informed consent.
Exclusion criteria
Exclusion criteria: One of the following conditions can be excluded: (1) Systemic or knee joint infection; (2) Congenital malformation, neuropathy and vascular disease cause dysfunction of lower extremity; (3) Patients with severe hip, ankle and low back pain; (4) persons with mental illness; (5) With coagulation disorders, gout, connective tissue and other diseases; (6) Knee joint diseases caused by systemic diseases; (7) Ozone allergy; (8) The intervention side of the knee has a history of surgery; (9) Bleeding or turbid joint effusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;WOMAC score; | — |
Secondary
| Measure | Time frame |
|---|---|
| SF-36;PHQ-9;GAD-7; | — |
Countries
China
Contacts
Public ContactXiaohong Jin
The First Affiliated Hospital of Soochow University
Outcome results
None listed