Hypertrophic scar
Conditions
Interventions
trial group:Carbon dioxide fractional laser combined with recombinant human type III collagen hydrogel
control group:Carbon dioxide fractional laser
Sponsors
Shanghai Changhai Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 99 Years
Inclusion criteria
Inclusion criteria: (1) The scar area is less than 5% TBSA, regardless of gender; (2) The scar has been formed for more than 6 months without signs of withdrawal; (3) Scar length >= 8cm, thickness >= 2mm; (4) The part of the scar is flat and the movement is small; (5) Good patient compliance; (6) No laser treatment contraindications; (7) The patient and his family members sign a written informed consent.
Exclusion criteria
Exclusion criteria: (1) The lesions are keloids or keloid tendencies, such as exceeding the original injury edge, irregular boundaries, infiltration into the surrounding normal tissues, and keloid growth; (2) Chronic wounds such as chemical burns, electric burns, diabetes, etc.; (3) Those who are known to have a history of allergies or allergies (allergic to 2 or more allergens) to the ingredients or other chemical structures contained in this product and the reference substance or topical anesthetics; (4) Severe malnutrition, albumin 38.5 degrees C or white blood cell > 12 * 10^9/L; (6) Those who have a serious systemic infection and need to be treated with antibiotics throughout the body; (7) Tumor, radiotherapy or chemotherapy patients; (8) Patients with severe primary diseases and mental illnesses such as cardiovascular, liver, kidney and blood system; (9) Pregnant or lactating women and those who have birth plans; (10) Those who have participated in other clinical research within 1 month before being selected; (11) There are situations in which other researchers think it is inappropriate to participate in clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in cross-sectional area of scar;POSAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Scar recurrence rate; | — |
Countries
China
Contacts
Public ContactSun yu
Shanghai Changhai Hospital
Outcome results
None listed