knee osteoarthritis/ knee rheumatoid arthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Eligible patients will be those scheduled for an elective unilateral, primary TKA, aged 18 to 80 years, and American Society of Anesthesiologists Physical Status classification I-III.
Exclusion criteria
Exclusion criteria: Contraindication to regional anesthesia or peripheral nerve blocks, allergy to local anesthetics, allergy to nonsteroidal anti-inflammatory drugs (NSAIDs), chronic renal insufficiency (Cr > 1.4 mg/dL or glomerular filtration rate 3 months), pre-existing peripheral neuropathy involving the operative site, and body mass index > 40 kg/m2.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| baseline characteristics of patients (age,gender, weight, height, surgery side, VAS pain score, Knee range of motion, quadriceps strength, ASA status, duration of operation;haematological indicators (CRP, IL-6, fasting blood-glucose);visual analogue scale pain score and rescue analgesia;postoperative functional recovery(degree of knee range of motion, quadriceps strength, daily mobilization);postoperative adverse events; | — |
Countries
China
Contacts
West China Hospital, Sichuan University