Safety and efficacy of stromal vascular fraction in the treatment of thin endometrium

Efficacy and safety of autologous adipose tissue-derived stromal vascular fraction in patients with thin endometrium: a protocol for a single center, longitudinal, prospective self-control study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035126

Enrollment

Unknown

Registered

2020-08-01

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thin endometrium

Interventions

SVF Group:SVF treatment

Eligibility

Sex/Gender

Female

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Infertile patients diagnosed with thin endometrium (less than 7mm on the day of ovulation or on the day of endometrial transformation in hormone replacement cycles); 2. Aged 20-45 years; 3. BMI with range of 22-29 kg/m2; 4. Patients with FSH < 15 IU/L or with frozen embryo.

Exclusion criteria

Exclusion criteria: 1. Patients that were diagnosed with moderate or severe adhesion (Patients with intrauterine adhesion can be included after being corrected the morphology of uterine cavity under hysteroscopy); 2. Infection of genitourinary system; 3. Uncontrolled systematic diseases; 4. Suspicious or underlying malignancy in both patients and their immediate family; 5. Alcohol or drug abuse.

Design outcomes

Primary

Measure	Time frame
Thickness of Endometrium;	—

Secondary

Measure	Time frame
Menstrual improvement;Pregnancy and offspring: clinical pregnancy rate, miscarriage, live birth rate;	—

Countries

China

Contacts

Public ContactRong Li

Reproductive Medicine Center, Peking University Third Hospital

roseli001@sina.com+86 15611908999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 10, 2026