Effects of low-dose dexamethasone on inflammatory factors in drainage fluid and wound healing after thyroid surgery during perioperative period

Effects of low-dose dexamethasone on inflammatory factors in drainage fluid and wound healing after thyroid tumor surgery during perioperative period

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035104

Enrollment

Unknown

Registered

2020-07-31

Start date

2020-08-03

Completion date

Unknown

Last updated

2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid tumor

Interventions

Dexamethasone group:Dexamethasone intravenously after general anesthesia

Saline group:Saline intravenously after general anesthesia

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients who underwent thyroid cancer resection in the thyroid group of general surgery of Shanghai Sixth People's Hospital from August 2020 to September 2020; 2. ASA grade I - II; 3. Patients aged between 20 and 65 years; 4. Patients with informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with thyroid tumor and grave's disease; 2. Patients with a history of second or more thyroid surgeries; 3. Patients with non-traditional neck incision; 4. Patients with history of head and neck surgery or radiotherapy; 5. Patients with laryngitis; 6. Patients with long history of glucocorticoid use; 7. Patients with diabetes mellitus; 8. Current pregnant or lactating patients; 9. Patients who are participating in other clinical trials.

Design outcomes

Primary

Measure	Time frame
IL-6;IL-10;	—

Secondary

Measure	Time frame
Postoperative wound healing score;	—

Countries

China

Contacts

Public ContactZhou Quanhong

Shanghai Sixth People's Hospital

zhouanny@hotmail.com+86 13761441463

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026