knee osteoarthritis
Conditions
Interventions
No tourniquet group:don't use tourniquet
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Primary knee osteoarthritis was diagnosed by symptoms, physical examination and imaging examination, with X-ray K-L stage III or above; (2) With severe knee pain, limited function and ineffective conservative treatment, unilateral primary knee replacement was planned; (3) No severe varus or valgus of knee joint (< 20 degrees).
Exclusion criteria
Exclusion criteria: (1) Previous long-term use of anticoagulant drugs for cardiovascular and cerebrovascular diseases for more than 3 months without stopping (aspirin/clopidogrel = 25.3mmol/L or blood creatinine >= 442umol/L), liver insufficiency (ALT or AST >= 80U/L), severe heart disease (or coronary stent implantation in the last 12 months), severe respiratory diseases (pulmonary function FEV1.0 = 46 seconds or INR >= 1.7)or history of stroke and malignant tumor. (2) Refusing to sign the informed consent form for not accepting this trial for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thickness of quadriceps;Hardness of quadriceps;Thigh circumference;HSS (Hospital of Special Surgery Score) and WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index);total blood loss;Visual analogue scale;Isokinetic strength;Three-dimensional gait;Balance posture;hemoglobin;hematocrit;C-Reactive Protein;D-Dimer;operating time; | — |
Secondary
| Measure | Time frame |
|---|---|
| time of using tourniquet; | — |
Countries
China
Contacts
Public ContactYang Li
Peking University Third Hospital
Outcome results
None listed