Irritable bowel syndrome
Conditions
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. It meets the diagnostic criteria of Western medicine for IBS and the type is diarrhea-based; 2. Patients with syndrome of liver depression and spleen deficiency in TCM differentiation; 3. Those who are rated as mild or moderate by IBS-SSS disease severity, that is, the IBS-SSS score is 76-300; 4. Patients with mild or moderate depression or anxiety evaluated by GAD-7 or PHQ-9, that is, those who have a total score of 5-15 for GAD-7 or 5-13 for PHQ-9; 5. Those who are willing to sign an informed consent; 6. Age between 18 and 70 years old; 7. Normal cognitive function, no literacy barriers; able to actively cooperate and participate in investigation and research.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant or preparing to become pregnant, and breastfeeding women; 2. Intestinal organic diseases, such as inflammatory bowel disease, intestinal tuberculosis, colon polyps; 3. Patients with severe cardiovascular and cerebrovascular system, liver, kidney, hematopoietic system diseases and tumors; 4. There is a record report of digestive tract surgery; 5. Patients with severe primary diseases and mental illnesses; 6. Patients who have taken psychiatric drugs, sleeping pills, anticholinergics, hormones, non-steroidal anti-inflammatory drugs and other drugs in the past 2 weeks, and received psychobehavioral therapy; 7. Patients with a history of allergy to related drugs used in this research; 8. Test results during the screening period showed that the ALT and AST values ??exceeded the upper limit of the normal range by 2 times, and the total bilirubin and BUN values ??exceeded the upper limit of the normal range by 1.5 times.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AR response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| PHQ-9;GAD-7;IBS-QOL;PSQI;Improvement of stool characteristics;TCM syndrome curative effect; | — |
Countries
China
Contacts
Public ContactHuang Shaogang
Guangdong Hospital of Traditional Chinese Medicine
Outcome results
None listed