A Cohort Study on Occurence, Pedigree Screening and Genetic Investigation of Bicuspid Aortic Valvular Disease (ORIENT-BAV Study)

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000035068

Enrollment

Unknown

Registered

2020-07-30

Start date

2016-07-21

Completion date

Unknown

Last updated

2020-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bicuspid Aortic Valvular Disease

Interventions

Case series:None

Eligibility

Sex/Gender

All

Age

5 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 5 to 75 years old; 2. Patients diagnosed by echocardiography examination previously with the conclusion of bicuspid aortic valvular disease, and their first-degree relatives (i.e. their parents, siblings,and children); 3. Subjects voluntarily participate in the study with signed informed consent; 4. The parents/legal guardians of the minor subjects agree to participate in the study with signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant woman or lactating woman; 2. Patients who cannot cooperate or are reluctant to sign the informed consent; 3. For minor patients, their parents or legal guardians do not agree to participate in the study.

Design outcomes

Primary

Measure	Time frame
Echocardiography;	—

Secondary

Measure	Time frame
Blood chemistry;	—

Countries

China

Contacts

Public ContactXiangqing Kong

The First Affiliated Hospital of Nanjing Medical University/ Jiangsu Province Hospital

kongxq@njmu.edu.cn+86 13951610265

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026