atiral fibrillation
Conditions
Interventions
amiodarone group:Operioperative infusion of amiodarone
Sponsors
The First Affiliated Hospital with Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Subjects undergoing VATS ablation for AF; 2. Aged between 18 to 70 years; 3. Nonvalvular AF; 4. American Society of Anesthesiologists (ASA) class I-III; 5. New York Heart Association (NYHA) class I-III.
Exclusion criteria
Exclusion criteria: 1. Preoperative use of class I or III antiarrhythmic drugs; 2. QTc>= 480ms or QT>= 500ms; 3. Mean heart rate of 24 hours 50mm; 5. Left ventricular ejection fraction <30%; 6. With high grade or III° atrioventricular block; 7. With thyroid dysfunction; 8. With rheumatic valvular disease; 9. Previous valvular replacement or valvuloplasty; 10. With left atrial appendage thrombosis; 11. With electrolyte imbalances; 12. With hepatic or renal dysfunction; 13. With pulmonary fibrosis; 14. Allergic to amiodarone.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Freedom from atrial arrhythmias 24 hours after the procedure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate change intraoperatively and postoperatively;Heart rhythm change intraoperatively and postoperatively;ventilation time;length of hospital stay; | — |
Countries
China
Contacts
Public ContactYin Fang
Outcome results
None listed