Efficacy of non-steroidal anti-inflammatory drugs in multimodal analgesia after cesarean section

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035010

Enrollment

Unknown

Registered

2020-07-27

Start date

2020-09-11

Completion date

Unknown

Last updated

2020-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after cesarean section

Interventions

Basic treatment group:TAP+ Butorphanol tartrate injection 0.2mg/h PCIA 48h

Group A1:TAP+ Butorphanol tartrate injection 0.2mg/h PCIA+ intravenous flurbiprofen axetil 50mg q12h 48h

Group A2:TAP+ Butorphanol tartrate injection 0.1mg/h PCIA+ intravenous flurbiprofen axetil 50mg q12h 48h

Group B1:TAP+ Butorfenol tartrate injection 0.2mg/h PCIA+ acetaminophen tablets 0.5g q6h + Ibuprofen tablets 0.1g Q6h orally 48h

Group B2:TAP+ Butorfenol tartrate injection 0.1mg/h PCIA+ acetaminophen tablets 0.5g q6h + Ibuprofen tablets 0.1g Q6h orally 48h

Group C1:TAP+ butorfenol tartarate injection 0.2mg/h PCIA+200mg flurbiprofen axetil injection PCIA 48h

Group C2:TAP+ butorfenol tartarate injection 0.1mg/h PCIA+200mg flurbiprofen axetil injection PCIA 48h

Group D1:TAP+ Butorfenol tartrate 0.2mg/h PCIA+ intravenous flurbiprofen 50mg q12h 24h+ acetaminophen tablets 0.5g Q6h + Ibuprofen tablets 0.1g Q6h 24h

Group D2:TAP+ Butorfenol tartrate 0.1mg/h PCIA+ intravenous flurbiprofen 50mg q12h 24h+ acetaminophen tablets 0.5g Q6h + Ibuprofen tablets 0.1g Q6h 24h

Eligibility

Sex/Gender

Female

Age

22 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. All patients aged >= 22 years who were to receive cesarean section in the department of obstetrics of our hospital received transverse abdominal muscle nerve block anesthesia and intravenous controlled analgesia after operation. 2. The patients and their family members were enrolled voluntarily and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Exclude patients who are at high risk of gastrointestinal ulcer, kidney injury, or cardiovascular adverse events and should not use nsAIDS; 2. Exclude patients who cannot use opioids due to allergy or other reasons.

Design outcomes

Primary

Measure	Time frame
Resting state pain assessment score;Functional activity state pain assessment score;	—

Countries

China

Contacts

Public ContactWei Lei

Women and Infans Hospital of Zhengzhou

leiwei3511@163.cm+86 15838325760

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026