Children with Autism Spectrum Disorder (ASD)
Conditions
Interventions
experimental group:BF839
Control group:placebo
Sponsors
The Second Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 10 Years
Inclusion criteria
Inclusion criteria: 1. Signing informed consent voluntarily; 2. The age is 2-10 years old (including 2 and 10 years old), with no gender limit; 3. Patients diagnosed with autism spectrum disorders in children according to the diagnostic and Statistical Manual of mental disorders (Fifth Edition, dsm-5) of the United States, or patients holding the diagnostic certificate of autism spectrum disorders of the Third Affiliated Hospital of Sun Yat sen University. 4. No antibiotics, probiotics, ketogenic diet, fecal bacterial transplantation, proton pump and other treatments affecting gastrointestinal tract were received within one month before enrollment. 5. Be able to receive follow-up visit, follow-up examination and specimen collection on time.
Exclusion criteria
Exclusion criteria: 1. The treatment plan (including any treatment) was just changed in the past month. 2. Other clinical trials were conducted within one month; 3. Children have schizophrenia, depression or organic brain dysplasia, brain tumors; 4. Children suffer from other unstable or serious heart, lung, liver, kidney and hematopoietic system diseases (including unstable angina pectoris, uncontrollable asthma, active gastric bleeding, cancer, etc.); 5. The guardian of the child did not agree to participate in the follow-up study or follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ABC scale;CARS scale;SRS scale;Social life ability scale for 0-year-old junior high school students;GSRS;CBCL scale; | — |
Countries
China
Contacts
Public ContactLin Chuhui
The Second Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed