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Comparison of wall removal type versus wall retaining type of decompression for treating large mandibular odontogenic cysts: a randomized controlled trial

Comparison of wall removal type versus wall retaining type of decompression for treating large mandibular odontogenic cysts: a randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035000
Enrollment
Unknown
Registered
2020-07-27
Start date
2020-08-01
Completion date
Unknown
Last updated
2020-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mandibular odontogenic cysts

Interventions

trial group:decompression with wall removed
control group:decompression with wall retained

Sponsors

The Ninth People's Hospital Affiliated to Medical School of Shanghai Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The patients with mandibular cyst were selected; 2. Patients aged 18-75 years; 3. The patients with more than 3 teeth positions or cyst with a maximum length of more than 3cm; 4. The continuity of mandible was intact. The thickness of lateral bone of cyst was more than 5mm (thickness of mandibular cortex); 5. Subjects with good general condition and no abnormal bone disease; 6. The subjects who voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with small cyst volume, unsuitable for fenestration, or with large cyst volume, causing extensive damage to mandible, interruption of mandible continuity and poor prognosis of fenestration and decompression; 2. The imaging features of the cyst were unclear margin, undercutting type, suspected to be malignant tumor of mandible, or patients with malignant tumor of mandible confirmed by postoperative pathology; 3. Patients with simple bone cyst without cyst wall coating; 4. Patients with mandibular myxoma; 5. Patients with severe mental illness, such as schizophrenia, depression, anxiety, etc., who are difficult to cooperate with clinical trials; 6. Patients with unclear description of self symptoms or uncooperative investigation; 7. Patients who received radiotherapy and chemotherapy due to other oral malignancies within 1 year after operation.

Design outcomes

Primary

MeasureTime frame
Percentage of the residual cyst volume within 1 year after surgery;

Countries

China

Contacts

Public ContactXingjun Qin

The Ninth People's Hospital Affiliated to medical school of Shanghai Jiaotong University

qinxj1989@sina.com+86 13621606535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026