Clinical evaluation of continuous plasma filtration adsorption in the treatment of sepsis with acute renal injury

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000034989

Enrollment

Unknown

Registered

2020-07-26

Start date

2020-09-01

Completion date

Unknown

Last updated

2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis with acute renal injury

Interventions

Group 1:continuous plasma filtration adsorption

Group 2:Continuous hemofiltration

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The diagnosis meets the diagnostic criteria for acute kidney injury in sepsis and the KDIGO guidelines; 2. Aged 18-65 years; 3. Participate in the clinical trial voluntarily and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with chronic maintenance dialysis; 2. Having mental illness and not cooperating in treatment; 3. Pregnant and lactating women; 4. Critically ill patients who are expected to die within 24 hours or who have been treated less than 24 hours; 5. Patients with active bleeding or severe bleeding tendency; 6. Long-term use of immunosuppressants or immunodeficiency; 7. Previous intolerance to blood purification treatment and allergy to other extracorporeal circulation treatment.

Design outcomes

Primary

Measure	Time frame
C-reactive protein;TNF-a;IL-6;IL-8;IL-10;28 days survival rate;Recovery rate of renal function;	—

Secondary

Measure	Time frame
90 days survival rate;	—

Countries

China

Contacts

Public ContactNan Chen

Shanghai Public Health Clinical Center

chennan@shphc.org.cn+86 18916506603

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026