preeclampsia/eclampsia
Conditions
Interventions
Gold Standard:Clinical outcome
Index test:MELODY kit
Sponsors
Sichuan University West China Second University Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years, normal understanding ability, no learning difficulties or mental illness; 2. informed and written consent; 3. live fetus at 11-14 weeks of gestation; 4. singleton pregnancies.
Exclusion criteria
Exclusion criteria: 1. Women with uterine abnormality 2. Women with HIV, HBV,HCV or Treponema pallidum positive 3. Women with benign or malignant tumors during pregnancy (except for physiological ovarian cysts and/or single uterine fibroids under the serous membrane (diameter<5cm)) 4. Women with chemotherapy or radiotherapy history 5. Women taking aspirin or other non-steroidal anti-inflammatory drugs or women took aspirin or other non-steroidal anti-inflammatory drugs within 28 days before enrolment 6. Women with chronic heart diseases or liver failure, kidney failure, respiratory failure, epilepsy, infectious gynecological diseases 7. Women with blood transfusion history within four weeks before enrolment 8. Women with history of organ transplantation, allogeneic cell therapy or stem cell therapy 9. Pregnancies complicated by major fetal abnormality identified at the 11-13 weeks assessment 10. Participation of other drug clinical trials within 3 months before enrolment 11. other conditions that clinical investigators think will decrease the quality of clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Pressure;urinary protein;renal and liver function;blood coagulation function;fetal growth restriction; | — |
Secondary
| Measure | Time frame |
|---|---|
| preterm;OGTT;HbA1C;thyroid function;Apgar Score; | — |
Countries
China
Contacts
Public ContactXinghui LIU
West China Second University Hospital, Sichuan University
Outcome results
None listed