Androgenic alopecia
Conditions
Interventions
Experimental group:5% minoxidil solution, 1ml for external application each time,twice a day for 6 months. On this basis, it is combined with local injection of PRP, 0.15 ml/cm2 each time, monthly, 3
Control group:5% minoxidil solution, 1ml for external application each time, twice a day for 6 months. On this basis, it is combined with local injection of 0.9% normal saline, 0.15 ml/cm2 each time,
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
Male
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. The typical clinical manifestations were consistent with the diagnosis of AGA, and the degree of alopecia accorded with the BASP classification of androgenic alopecia; 2. Patients with good general condition (no previous heart, systemic, scalp diseases) did not use any drugs that may affect hair growth (antihypertensive drugs, hormones, cytotoxic drugs, drugs with anti androgen effect, etc.) within 3 months before the study; 3. Patients who agree to participate in observation and follow-up, are willing to accept follow-up and can cooperate closely in the whole process.
Exclusion criteria
Exclusion criteria: 1. Patients who took finasteride orally within 18 months before the start of the trial; 2. Patients who use local or systemic drugs that affect hair growth within 12 months; 3. Patients with history of hair transplantation; 4. The patient's scalp may be affected by the growth of the scalp or the whole body.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Severity of Alopecia Tool, SALT;Evaluation of hair regeneration rate;The hair thickness and hair density of AGA patients before and after treatment are measured by Dermatoscope, and the improvement is judged by comparing the median hair density and width .;Evaluation of subjective satisfaction of patients;The quality of life (Qol) of patients is investigated by using the international dermatological quality of life questionnaire; | — |
Primary
| Measure | Time frame |
|---|---|
| The same photographic method, according to 7-point rating scale by P. Suchonwanit.; | — |
Countries
China
Contacts
Public ContactHuang Xin
Shanghai Tongji Hospital
Outcome results
None listed