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Effect of deep neuromuscular blockade and low pneumoperitoneum pressure on nociceptive recovery after major laparoscopic gastrointestinal surgery

Effect of deep neuromuscular blockade and low pneumoperitoneum pressure on nociceptive recovery after major gastrointestinal laparoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034957
Enrollment
Unknown
Registered
2020-07-25
Start date
2022-03-01
Completion date
Unknown
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recovery after major laparoscopic gastrointestinal surgery

Interventions

deep NMB + low IAP:deep neuromuscular block and low intra-abdominal pressure
Moderate NMB + standard IAP:Moderate neuromuscular blockand standard intra-abdominal pressure

Sponsors

Department of Anesthesiology, First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who are older than 18 years old, ASA grade I to III, and undergo elective major laparoscopic gastrointestinal surgery (>= 1.5 hours) under general anesthesia, with provision of written informed consent.

Exclusion criteria

Exclusion criteria: Emergency or unplanned surgery; pregnancy; severe cardiopulmonary, cerebrovascular, hepatic, or renal disease; immune system or neuromuscular disease; inability to cooperate or complete study questionnaires; or known allergies to the medications used in this study.

Design outcomes

Primary

MeasureTime frame
PQRS nociceptive domain;—

Secondary

MeasureTime frame
Recovery in other PQRS domains;recovery in all PQRS domains;—

Countries

China

Contacts

Public ContactKe Peng

The First Affiliated Hospital of Soochow University

pengke0422@163.com+86 15962155989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026