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Risk factors related to adverse effects in breast cancer patients after radiotherapy: a prospective cohort study

Risk factors related to adverse effects in breast cancer patients after radiotherapy: a prospective cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034946
Enrollment
Unknown
Registered
2020-07-25
Start date
2020-08-15
Completion date
Unknown
Last updated
2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast carcinoma

Interventions

Side effects group after radiotherapy vs no reaction group after radiotherapy:Nil

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) female sex and 18 years or older; 2) new diagnosis of breast carcinoma (stage 0 to III); 3) post-lumpectomy, -quadrantectomy, or -mastectomy; 4) plan to receive adjuvant radiotherapy (RT) to the whole breast or chest wall with or without regional lymph nodes (total dose >= 40 Gy, dose per fraction >= 2 Gy), use of intensity-modulated RT.

Exclusion criteria

Exclusion criteria: 1) prior radiation to the involved breast or chest wall; 2) concurrent chemotherapy; 3) immediate breast reconstruction after mastectomy; 4) partial breast irradiation; 5) planned use of skin-sparing intensity-modulated RT to treat the involved breast or chest wall.

Design outcomes

Primary

MeasureTime frame
C-Reactive Protein;

Secondary

MeasureTime frame
Blood routine;Serum iron;Ferritin;Total iron binding capacity;Transferrin saturation;Lymphocyte subsets (CD3+, CD4+, CD8+, CD19+, CD56+);Triglycerides;High density lipoprotein;Low-density lipoprotein;Blood uric acid;albumin;blood sugar;blood pressure;BMI;Abdominal circumference;

Countries

China

Contacts

Public ContactCheng Jing

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Chenjin1118@hotmail.com+86 13006178752

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026