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Research on MRI novel sequence of tumor heterogeneity and its diagnostic modeling with artificial intelligence

Research on MRI novel sequence of tumor heterogeneity and its diagnostic modeling with artificial intelligence

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034937
Enrollment
Unknown
Registered
2020-07-25
Start date
2020-07-25
Completion date
Unknown
Last updated
2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioma and prostate cancer

Interventions

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Sponsors

Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with glioma: 1. The age range of the experimental subjects is between 18 and 65 years old. 2. Gender is controlled at 1:1, 50 female glioma patients and 50 male glioma patients, 3. The condition is stable and there are no other metabolic diseases, brain trauma or comorbidities. 4. Brain tumor surgery will be performed within a month. 5. A transcranial magnetic resonance scan showed nodules no smaller than 1 cm. 6. The tumor site should be supracurvature glioma (cerebral hemispheric glioma) or subcurvature glioma (cerebellar glioma), including frontal lobe, parietal lobe, temporal lobe, occipital lobe, semi-oval center, basal ganglia, thalamus And corpus callosum tumors, or other types of brain tumors above and below the curtain. 7. Sign informed consent. Patients with prostate cancer: 1. The age range of the test subjects is between 18 and 65 years old. 2. The condition is stable and there are no other metabolic diseases, trauma or comorbidities. Prostate cancer surgery will be 2/. rformed within a month. 3. Plain magnetic resonance scan showed nodules no smaller than 0.5cm. 4. Sign informed consent.

Exclusion criteria

Exclusion criteria: Patients with glioma: 1. Exclude test subjects who cannot cooperate with the magnetic resonance examination due to their own reasons, such as metallic foreign bodies, claustrophobia or mental disorder. 2. Because the diffusion sequence is susceptible to magnetically sensitive artifacts, it excludes brainstem and spinal cord tumors, and types of brain tumors close to the sella, cerebellopontine angle, pituitary, skull base, and orbit. 3. Patients who have undergone conventional treatments for brain tumors such as surgery, medication, or radiotherapy. Patients with prostate cancer: 1. Exclude the test subjects who cannot complete the magnetic resonance examination due to their own reasons, such as metallic foreign bodies and claustrophobia. 2. Exclude patients who have undergone surgery, drug therapy, radiotherapy and other conventional tumor treatments.

Design outcomes

Primary

MeasureTime frame
AUC value;ROC curve;

Secondary

MeasureTime frame
F1-SOCRE;accuracy rate;recall rate;Precision-recall curve;Kolmogorov-Smirnov value;

Countries

China

Contacts

Public ContactHaibo Xu
xuhaibo1120@hotmail.com+86 13545009416

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026