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Characteristics of microbiota - intestinal - cerebral axis in feeding center and non-feeding center injury in patients with intracerebral hemorrhage

Effects of fecal transplantation on patients with severe craniocerebral injury and its mechanism

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034906
Enrollment
Unknown
Registered
2020-07-24
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intracerebral hemorrhage

Interventions

Feeding center group:none
None feeding center group:none
healthy group:none

Sponsors

South Campus, Renji Hospital Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed as ICH: diagnosed according to the AHA/ASA guidelines for the management of spontaneous cerebral hemorrhage in 2015; 2. Aged 18-70 years; 3. For those without civil capacity, the agent shall decide whether to participate voluntarily, and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Received broad-spectrum, long-term or combined anti-infection treatment 2. Have been exposed to antibiotics or immunosuppressant/hormone therapy within the last 3 months, and have autoimmune diseases 3. Previous history of gastrointestinal surgery and tumor, no history of gastrointestinal dysfunction such as chronic diarrhea, abdominal distension and constipation; 4. Previous history of cancer and diabetes.

Design outcomes

Primary

MeasureTime frame
Fecal flora genomics;survival rate Of 20 days;Disability level;Fecal flora;

Secondary

MeasureTime frame
Blood routine;hepatic and renal function;All blood Cells Analysis;APACHE II;PCT;GCS;Temperature;gastroenteric function;

Countries

China

Contacts

Public ContactTianyi Ai

South Campus, Renji Hospital Shanghai Jiaotong University School of Medicine

173163618@qq.com+86 13816870655

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026