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Efficacy and safety of trantranylic acid topical application for perioperative blood loss control in elderly patients undergoing PFNA for intertrochanteric fracture

Efficacy and safety of trantranylic acid topical application for perioperative blood loss control in elderly patients undergoing PFNA for intertrochanteric fracture

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034882
Enrollment
Unknown
Registered
2020-07-22
Start date
2020-07-17
Completion date
Unknown
Last updated
2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intertrochanteric fracture

Interventions

trial group:Topical use of tranexamic acid
control group:Apply the same amount of saline locally

Sponsors

The People's Hospital of Nanchuan, Chongqing
Lead Sponsor

Eligibility

Sex/Gender
All
Age
70 Years to 120 Years

Inclusion criteria

Inclusion criteria: (1) Aged >= 70 years at the time of injury; (2) X-ray and CT showed intertrochanteric fracture with AO classification; (3) PFNA system can be used to perform intertrochanteric fracture surgery as determined by senior professional orthopedic trauma doctors.

Exclusion criteria

Exclusion criteria: (1) Allergic to TXA or low molecular weight heparin; (2) Old, multiple or pathological fractures; (3) Severe heart, lung, liver, kidney or coagulation dysfunction; (4) Preoperative anticoagulant therapy such as antiplatelet drugs or warfarin should be applied; (5) Recent or ongoing thromboembolic events include deep vein thrombosis, pulmonary embolism, arterial thrombosis, cerebral thrombosis, or stroke; (6) Follow-up time <1 month.

Design outcomes

Primary

MeasureTime frame
bleeding;

Secondary

MeasureTime frame
complications;

Countries

China

Contacts

Public ContactWei Huiping
316487953@qq.com+86 15023927701

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026