A prospective comparative study of myocardial ischemia-reperfusion injuryreperfusion injury in patients with high and low altitude cardiac surgery and its relationship with HIF-1a/miR-210

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000034866

Enrollment

Unknown

Registered

2020-07-22

Start date

2020-07-31

Completion date

Unknown

Last updated

2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac ischemia-reperfusion injury

Interventions

High altitude group:Nil

Low altitude group:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing cardiac surgery in Sichuan Provincial People's Hospital from January 2021 to June 2021; 2. Aged >= 18 years; 3. Patients are willing to participate in the study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant women; 2. With coronary heart disease or atrial fibrillation; 3. With a history of myocardial infarction; 4. Non-cardiac arrest surgery.

Design outcomes

Primary

Measure	Time frame
HIF-1a;HIF-1a;	—

Secondary

Measure	Time frame
miR-210;miR-210;cTnI;cTnI;h-FABP;h-FABP;AI;AI;	—

Countries

China

Contacts

Public ContactWei Xinchuan

Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital

390626473@qq.com18980601553

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026