sedation
Conditions
Interventions
control group :0.1 ug/kg sufentanil+0.02 mg/kg midazolam +Isometric saline
low-dose lidocaine group :0.1 ug/kg sufentanil+0.02 mg/kg midazolam+1.5 mg/kg lidocaine tnen continuous infusion of 2 mg/kg/h
high-dose lidocaine group :0.1 ug/kg sufentanil+0.02 mg/kg midazolam+1.5 mg/kg lidocaine tnen continuous infusion of 4 mg/kg/h
Sponsors
Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with ASA I-II in our hospital, aged 18-70 years old undergoing ERCP. 2. Patients with informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with pre-existing hypoxemia, SpO2 170 mmHg, diastolic blood pressure >100 mm Hg); 4. Hemodynamically unstable patients; 5. Heart rate <50 beats/min; 6. Patients with atrioventricular block; 7. Severe renal or liver insufficiency; 8. Pregnant or breastfeeding; 9. Patients with a history of lidocaine allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total induction dose of propofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| haemodynamics;Ramsay score;Aldrete score;The total induction dose of flumazenil;The total induction dose of naloxone; | — |
Countries
China
Contacts
Public ContactFushan Xue
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed