Early diagnostic criteria for invasive fungal infection in severe burns: comparative study of next-generation sequencing technology detection and traditional method detection

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000034860

Enrollment

Unknown

Registered

2020-07-22

Start date

2020-08-01

Completion date

Unknown

Last updated

2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Invasive fungal infection in severe burns

Interventions

Gold Standard:Traditional method detection (Microbiological culture, histopathological examination, GM, BDG)

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Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-70 years, regardless of gender; 2. Burn patients (flame burn, electric burn, chemical burn, various hydrothermal burns) with a total area of 30% or more; 3. Patients admitted to hospital within 24 hours after burn; 4. Patients without infectious diseases; 5. Signing consent: all subjects voluntarily signed informed consent before the experiment.

Exclusion criteria

Exclusion criteria: Patients with severe immunodeficiency diseases, such as AIDS.

Design outcomes

Primary

Measure	Time frame
Observe whether relevant genes can be detected in gene sequencing when patients have invasive fungal infections;SEN, SPE, ACC, AUC of ROC;	—

Countries

China

Contacts

Public ContactWang Daoxin

The Second People's Hospital of Shenzhen

szwhe@sina.com+86 13662214896

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026