Painless colonoscopy
Conditions
Interventions
control group:normal saline
Experimental group 1:Butorphanol tartrate5ug/Kg
Experimental group 2:Butorphanol tartrate10ug/Kg
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. General anesthesia patients to undergo painless colonoscopy; 2. American Society of Anesthesiologists (ASA) classification ? ~ Grade; 3. Aged 18 to 65 years;
Exclusion criteria
Exclusion criteria: 1. Obstructive sleep apnea hypopnea syndrome (OSAHS); 2. Liver and renal failure; 3. Severe cardiovascular and cerebrovascular diseases (cardiac function NYHA>=3) 4. A history of chronic pain or mental illness; 5. People who are used to using sedatives and analgesics; 6. Patients with a history of vertigo or motion sickness; 7. Body mass index >= 30kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma concentration of TCI propofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia, hypotension and sinus bradycardia;Incidence of nausea and vomiting;Incidence of vertigo;Changes of mean arterial pressure (MAP) and heart rate (HR) at four time points before induction (T0), loss of consciousness (T1), colonoscopy at ileocecal region (T2), and consciousness recovery (T3);The amount of propofol used;Propofol effector chamber concentration during awakening; | — |
Countries
China
Contacts
Public ContactDefeng Sun
Department of Anesthesiology, the First Affiliated Hospital of Dalian Medical University
Outcome results
None listed