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The effects of repetitive transcranial magnetic stimulation combined with transcranial direct current stimulation on motor function and cortex excitability in subacute stroke patients

The effects of repetitive transcranial magnetic stimulation combined with transcranial direct current stimulation on motor function and cortex excitability in subacute stroke patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034846
Enrollment
Unknown
Registered
2020-07-21
Start date
2021-01-01
Completion date
Unknown
Last updated
2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

control group:Routine medications treatments
1Hz rTMS group:Routine medications and 1Hz rTMS stimulation treatments
cathodic tDCS combined with 1Hz rTMS group:Routine medications and cathodic tDCS combined with 1Hz rTMS stimulation treatments
anodic tDCS combined with 1Hz rTMS group:Routine medications and anodic tDCS combined with 1Hz rTMS stimulation treatments

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. In accordance with the diagnostic criteria of stroke (cerebral hemorrhage and cerebral infarction) formulated by the National Cerebrovascular Disease academic Conference; 2. The first onset of stroke with limb motor dysfunction was confirmed by CT and MRI, and the course of the disease was within 30 days; 3. MRI and intracranial vascular examination confirmed that the focus of stroke was the blood supply area of middle cerebral artery; 4. Motor evoked potentials (MEPs) could be recorded by stimulation in M1 area of the affected side.

Exclusion criteria

Exclusion criteria: 1. Patients with limb dysfunction caused by other nervous system diseases; 2. Patients with contraindications to rTMS therapy such as epilepsy and metal implants; and 3. Severe cognitive and mental disorders and inability to cooperate. All the patients enrolled in this study signed informed consent forms and related documents.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment score;NHI Stroke Scale;Barthel Index;Amplitude of Motor Evoked Potentials;resting Motion Threshold value;Central Motor Conduction Time;

Countries

China

Contacts

Public ContactMing Ye

The First Affiliated Hospital of Soochow University

20194132166@stu.suda.edu.cn+86 18994377195

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026