Colon cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 30-65 years; 2. ASA class II-III; 3. The diagnosis of colon cancer by pathological examination was consistent with the surgical indications; 4. The same surgical technique applied to all patients (The surgery was performed through a paramedian incision in the lower abdomen, the length of the incision site was about 13 cm, the length of the removed bowel was 15 cm or so, and the lymph nodes around the bowel and the root of mesentery were cleaned.); 5. Total intravenous anesthesia or combined QLB3 was applied to all operations; 6. All surgeries and anesthesia management were carried out by the same team; 7. Patients signed the informed consent form for 48-hour postoperative analgesia and sufentanil was used for emergency analgesia when PCIA was insufficient.
Exclusion criteria
Exclusion criteria: 1. Preoperative cognitive dysfunction; 2. Severe cardiopulmonary dysfunction; 3. Severe liver or kidney dysfunction(CHILD grade less than 10 and the creatinine at 451-707 mol /L respectively.); 4. Hematological system disease, coagulation abnormality or anticoagulation treatment; 5. Distant organ metastasis; 6. Recent take of analgesics; 7. Past history of abdominal surgery; 8. Regional block contraindications or complications; 9. Failure to complete data collection and follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the first time of getting up;the first time of anal exhaust;the first time of taking semi-liquid diet;postoperative hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative pain scores;Intraoperative and postoperative sufentanil dosage;Remifentanil dosage; | — |
Countries
China
Contacts
The Second Hospital of Shandong University