Knee Osteoarthritis (KOA)
Conditions
Interventions
Experimental group:electro-acupuncture with the top ten high-selected acupoints
control group 1:traditional acupuncture with the top ten high-selected acupoints
control group 2:electro-acupuncture with the acupoints not belonging to the main meridians
Sponsors
Universiti Tunku Abdul Rahman
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients are not suffering rheumatoid arthritis (RA), the results of the laboratory tests for rheumatoid factors are negative; 2) The patients are not in the acute phase of knee osteoarthritis and have not been accompanied by inflammatory lesions in the past two weeks, not taken antibiotics or hormonal drugs in the past two weeks; 3) Aged 45 to 80 years old; 4) Patients who meet the above diagnostic criteria; 5) Did not receive other related treatments within 1 month (or treatments that may affect the observation of the efficacy indicators of the study); 6) Can accept and adhere to the whole course of treatment; 7) The localized skin of the knee joint is intact; 8) Voluntary signing Informed consent and risk notification for acupuncture treatment of KOA.
Exclusion criteria
Exclusion criteria: 1) Those who do not meet the diagnostic criteria and the inclusion criteria; 2) Patients who have another relevant history of joint diseases, such as rheumatism, rheumatoid, gout disease, and any other type of arthritis or other knee painful diseases; 3) The patients are in the acute phase of knee osteoarthritis and have been accompanied by inflammatory lesions in the past two weeks, taken antibiotics or hormonal drugs in the past two weeks; 4) Visual analogue scale (VAS) <=3; 5) Knee joint disease caused by trauma, or local skin of the knee joint damage or with inflammation; 6) Blood, kidney, liver, and metabolic dysfunction. Or with mental illness or tumor; 7) Patients with systemic or local infections or infectious diseases; 8) Pregnancy or lactation women. And anyone with a cardiac pacemaker or any metal object in the body. 10) Patients with the symptoms of allergies, gastrointestinal discomfort, and other symptoms. 11) Researchers believe there are other reasons that are not suitable for clinical trials. 12) Patients who do not cooperate with follow-up work.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical comprehensive efficacy evaluation score;Level of IL-1beta and TNF-alpha in patients' serum; | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster University Osteoarthritis Index score (WOMAC);Lysholm knee scoring scale (LKSS);Visual Analogue Score/Scale (VAS); | — |
Countries
China
Contacts
Public ContactTe Kian Keong
Universiti Tunku Abdul Rahman
Outcome results
None listed